Fatty acid esters
Cayman Chemical Lauric Acid Fatty Acids and De
A medium-chain fatty acid; has been found at high levels in coconut oil; induces the activation of NF-κB and the expression of COX-2, iNOS, and IL-1α in RAW 264.7 cells at 25 µM
Apexbio Technology LLC (±)-Octanoylcarnitine chloride 14919-35-8 100mg
( )-Octanoylcarnitine chloride is an acyl derivative structurally related to acetylcarnitine chloride it functions as an intermediate in fatty acid metabolism by facilitating fatty acid transport across mitochondrial membranes for subsequent -oxidation and ATP synthesis Experimental evidence indicates that ( )-octanoylcarnitine modulates mitochondrial utilization of certain branched-chain 2-oxo acids influencing their oxidation rates in isolated mitochondria Additionally researchers employ ( )-octanoylcarnitine combined with malate to investigate mitochondrial respiratory activity examining oxidative phosphorylation dynamics in response to metabolic modulators such as ADP and creatine particularly in isolated cardiac muscle tissues
Apexbio Technology LLC Monomethyl auristatin E 474645-27-7 10mM (in 1mL DMSO)
Monomethyl auristatin E (MMAE) is a highly potent antimitotic compound that exerts cytotoxic effects by inhibiting tubulin polymerization Microtubules play essential roles in various cellular processes including intracellular transport cell migration and mitotic chromosome segregation MMAE interrupts this process leading to cell cycle arrest and apoptosis MMAE is commonly utilized in preclinical and clinical studies as the cytotoxic payload in antibody-drug conjugates (ADCs) targeting tumor-specific antigens to selectively deliver cytotoxicity to cancer cells In vitro cell studies and in vivo tumor xenograft models show that antibody conjugation enables specific targeting resulting in reduced off-target toxicity and improved therapeutic index compared to unconjugated cytotoxic agents
AdipoGen Resorufin butyrate
Chemical. CAS 15585-42-9. Formula C16H13NO4. MW 283.28. Synthetic. Suitable as fluorogenic substrate for lipases, choline esterases.
Apexbio Technology LLC Monomethyl auristatin E 474645-27-7 5mg
Monomethyl auristatin E (MMAE) is a highly potent antimitotic compound that exerts cytotoxic effects by inhibiting tubulin polymerization Microtubules play essential roles in various cellular processes including intracellular transport cell migration and mitotic chromosome segregation MMAE interrupts this process leading to cell cycle arrest and apoptosis MMAE is commonly utilized in preclinical and clinical studies as the cytotoxic payload in antibody-drug conjugates (ADCs) targeting tumor-specific antigens to selectively deliver cytotoxicity to cancer cells In vitro cell studies and in vivo tumor xenograft models show that antibody conjugation enables specific targeting resulting in reduced off-target toxicity and improved therapeutic index compared to unconjugated cytotoxic agents
Apexbio Technology LLC Monomethyl auristatin E 474645-27-7 1mg
Monomethyl auristatin E (MMAE) is a highly potent antimitotic compound that exerts cytotoxic effects by inhibiting tubulin polymerization Microtubules play essential roles in various cellular processes including intracellular transport cell migration and mitotic chromosome segregation MMAE interrupts this process leading to cell cycle arrest and apoptosis MMAE is commonly utilized in preclinical and clinical studies as the cytotoxic payload in antibody-drug conjugates (ADCs) targeting tumor-specific antigens to selectively deliver cytotoxicity to cancer cells In vitro cell studies and in vivo tumor xenograft models show that antibody conjugation enables specific targeting resulting in reduced off-target toxicity and improved therapeutic index compared to unconjugated cytotoxic agents
Selleck Chemical LLC D-Carnitine hydrochloride
D-Carnitine hydrochloride ((S)-Carnitine hydrochloride ( )-Carnitine hydrochloride) is biosynthesized from lysine It might be associated with the energy production from branched chain amino acids
AdipoGen 4-Methylumbelliferyl palmitate
Chemical. CAS 17695-48-6. Formula C26H38O4. Molecular Weight 414.59. 4-Methylumbelliferyl palmitate 4-MUP is a fluorogenic substrate for lysosomal acid lypase LAL. 4-MUP is cleaved by LAL or by other acid lipases to release the fluorescent moiety 4-MU. Recent advances allow the assessment of LAL activity in very small blood volumes using 4-MUP. Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase LAL, also known as cholesteryl ester hydrolase. Spectral data 4-MU fluorescence is pH-dependent. lambdaex 320nm pH 1.97-6.72 and 360nm pH 7.12-10.3 lambdaem 445-455nM increasing as pH decreases.
AdipoGen 4-Methylumbelliferyl heptanoat
Chemical. CAS 18319-92-1. Formula C17H20O4. MW 288.34. Synthetic. Fluorogenic substrate for lipases.
Selleck Chemical LLC Doxylamine Succinate S4240-50mg
Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects
eMolecules Benzyl isovalerate | 103-38-8 | MFCD00048348 | 25g
Combi-Blocks, Inc. | Benzyl isovalerate | 25g | 603138663 | QF-8296 | 95.000 | 103-38-8 | MFCD00048348 | 192.258 | C12H16O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules Phenethyl octanoate | 5457-70-5 | MFCD00209536 | 25g
Combi-Blocks, Inc. | Phenethyl octanoate | 25g | 603138954 | QH-1730 | 95.000 | 5457-70-5 | MFCD00209536 | 248.366 | C16H24O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
TARGETMOL CHEMICALS INC L-Octanoylcarnitine 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes.L-Octanoylcarnitine is the active octanoylcarnitine present in plasma and is a potential biomarker for breast cancer. Purity 99.63%